One class of copper-free click-chemistry reactions will be the [4 + 2] cycloadditions between an electron-rich dienophile like a trans cyclooctene (TCO) or a bicyclononyne (BCN) and an electron-deficient diene (tetrazine), also known as an inverse electron-demand Diels-Alder (IEDDA)
One class of copper-free click-chemistry reactions will be the [4 + 2] cycloadditions between an electron-rich dienophile like a trans
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